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Postdoctoral Fellow

Job Field: Government Jobs
Location: PORTLAND, WA
Salary: $-
Job Type: Part Time
JOB SUMMARY:
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               <td align="left"><font style="font-size: 100%;">Postdoctoral Fellow<BR> <BR>Department Dermatology<BR> <BR>Location SJH 5308<BR> <BR>Work Unit Description <BR> <BR> <BR> <BR>Work Schedule, Hours, FTE, Salary Range <BR> <BR> 1.0 FTE; Salary Range: depending on experience, NIH stipend levels.<BR> <BR>Functions/Duties of Position <BR> <BR> This Postdoctoral training opportunity available now to study keratinocyte cancer evolution and skin homeostasis. Mouse in vitro/in vivo skin graft, transgenic and knock-out models are being used to define early events that are maintained or further altered in malignancy, as predictors of outcomes and as targets for molecular therapies for epithelial solid tumors of skin and head & neck. The position offers opportunity for fellowship on an NCI Training Program on the Molecular Basis of Skin/Mucosa Pathobiology. Methods and approaches include specialized epidermal cell culture, genetic mouse models, immunostaining, live cell imaging of fluorescent tagged proteins, chromatin immunoprecipitation, cell based, and cell free recombinant, protein-protein interaction, ubiquitylation and sumoylation assays, luciferase reporter assays and cell fate assays (e.g. cell death mechanism, proliferation), as well as translational evaluation of cytokine, protein/antigen expression and protein activity in human biopsy specimens. Additional approaches include microarray, genetic polymorphisms/sequencing of relevant genes and preclinical assessment of small molecules to interfere with E3 ligase regulated pathways. Our program offers opportunity for future translation of basic research to clinical trial. See for more information:http://www.ohsu.edu/xd/research/research-expertise/researchers/kuleszma.cfm andhttp://www.ohsu.edu/xd/education/schools/school-of-medicine/departments/clinical-departments/dermatology-research/research-training-program/index.cfm<BR> <BR>Job Requirements <BR> <BR> Postdoctoral trainees will be selected who desire an academic career in cancer research making use of advantages of surface epithelial models, with a strong clinical translational component. Criteria will include potential for independence, letters of recommendation, publication record and evidence of potential for impact in dermatology or solid tumors. Must be US Citizen or Permanent Resident and able to start before August 31, 2010.<BR> <BR>Additional Details <BR> <BR> <BR> <BR>How To Apply <BR> <BR> To apply: Send by email cover letter, statement of research (current and future interests and aims), CV, and three letters of reference to: Molly Kulesz-Martin, PhD, at dermres@ohsu.edu. OHSU is an equal opportunity employer.<BR> <BR>Referral Bonus Eligible <BR>Referral Bonus Amount <BR> <BR><BR><BR><BR><BR><BR><BR>Documents<BR><BR><BR><BR><BR><BR><BR><BR><BR><BR><BR><BR>Title<BR>Type<BR>Description<BR>Category<BR>Last Updated By<BR>Last Updated<BR>Usage<BR>Update<BR>Delete<BR>No results found.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             </font></td>
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